Mr. Nasheed has cerebral palsy and suffers severe skeletal muscle spasms as a result of his condition. He is prescribed the drug dantrolene, which prevents the release of Ca2+ from the SR. Explain how this will treat his muscle spasms.
Table of contents
- 1. Introduction to Anatomy & Physiology5h 43m
- What is Anatomy & Physiology?22m
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- 29. Heredity3h 32m
9. Muscle Tissue
Structure of a Skeletal Muscle
Problem 21
Textbook Question
Compartment syndrome can result from all of the following except
(a) Compressing a nerve in the wrist
(b) Compartments swelling with blood due to an injury involving blood vessels
(c) Torn ligaments in a given compartment
(d) Pulled tendons in the muscles of a given compartment
(e) Torn muscles in a particular compartment

1
Step 1: Understand the concept of compartment syndrome. Compartment syndrome occurs when increased pressure within a muscle compartment (a group of muscles, nerves, and blood vessels surrounded by fascia) restricts blood flow and damages tissues. It is typically caused by swelling, bleeding, or injury within the compartment.
Step 2: Analyze the options provided in the question. Each option describes a potential cause or condition related to compartment syndrome. You need to identify the one that does not align with the typical causes of compartment syndrome.
Step 3: Evaluate each option:
(a) Compressing a nerve in the wrist: This is not directly related to compartment syndrome, as it involves nerve compression rather than pressure within a muscle compartment.
(b) Compartments swelling with blood due to an injury involving blood vessels: This is a common cause of compartment syndrome.
(c) Torn ligaments in a given compartment: Ligament injuries can contribute to swelling and pressure, potentially leading to compartment syndrome.
(d) Pulled tendons in the muscles of a given compartment: Tendon injuries are less likely to cause compartment syndrome directly, as they do not typically lead to significant swelling or pressure.
(e) Torn muscles in a particular compartment: Muscle tears can cause bleeding and swelling, which are common causes of compartment syndrome.
Step 4: Compare the options and identify the one that does not fit the typical causes of compartment syndrome. Focus on whether the described condition leads to increased pressure within a muscle compartment.
Step 5: Conclude that the correct answer is the option that does not align with the mechanism of compartment syndrome. Ensure you understand why the other options are valid causes and why the chosen option is not.

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Compartment Syndrome
Compartment syndrome is a serious condition that occurs when pressure within a muscle compartment increases, leading to reduced blood flow and potential muscle and nerve damage. It can result from trauma, swelling, or tight bandaging, and is characterized by severe pain, swelling, and sometimes loss of function in the affected area.
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Anatomy of Compartments
Muscle compartments are groups of muscles, nerves, and blood vessels surrounded by a tough membrane called fascia. Each compartment has a limited capacity to expand, and when swelling occurs due to injury or inflammation, it can lead to increased pressure, compromising circulation and nerve function within that compartment.
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Causes of Compartment Syndrome
Compartment syndrome can be caused by various factors, including trauma (like fractures), excessive exercise, or conditions that lead to bleeding or swelling within a compartment. Understanding these causes helps in identifying potential scenarios that could lead to this condition, allowing for timely intervention and treatment.
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