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Multiple Choice
Which of the following is true regarding complementary base pairing in DNA and RNA molecules?
A
Although a DNA molecule demonstrates complementary base pairing between two DNA polynucleotides to form a double helix, an RNA molecule can base-pair only along stretches of nucleotides in the same RNA molecule, such as in transfer RNA molecules.
B
Complementary base pairing promotes an antiparallel orientation in the structure of DNA and RNA molecules.
C
Complementary base pairing within single strands of DNA and RNA gives them particular three-dimensional structures that are necessary for their function.
D
None of the listed responses is correct.
E
Although the base pairing between two strands of DNA in a DNA molecule can be thousands to millions of base pairs long, base pairing in an RNA molecule is limited to short stretches of nucleotides in the same molecule or between two RNA molecules.
Verified step by step guidance
1
Understand the concept of complementary base pairing: In DNA, complementary base pairing occurs between two strands, forming a double helix. The bases pair specifically: adenine (A) with thymine (T), and cytosine (C) with guanine (G). In RNA, adenine pairs with uracil (U) instead of thymine.
Recognize the structural differences between DNA and RNA: DNA is typically double-stranded, allowing for long stretches of complementary base pairing. RNA is usually single-stranded, but can form short stretches of base pairing within the same molecule or between two RNA molecules.
Consider the role of complementary base pairing in the structure and function of nucleic acids: In DNA, base pairing contributes to the stability and replication of the double helix. In RNA, base pairing can influence the molecule's three-dimensional structure, which is crucial for its function, such as in tRNA or rRNA.
Evaluate the statement regarding antiparallel orientation: Complementary base pairing in DNA results in an antiparallel orientation, where the two strands run in opposite directions. This is a key feature of DNA structure but is not applicable in the same way to RNA.
Analyze the given options: The correct answer highlights the difference in base pairing length between DNA and RNA. DNA can have extensive base pairing across its double strands, while RNA base pairing is limited to shorter stretches within or between RNA molecules.