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Multiple Choice
Which of the following events occur during prometaphase of mitosis?
A
Chromosomes align at the metaphase plate.
B
Sister chromatids separate and move to opposite poles.
C
The cell grows and duplicates its DNA.
D
The nuclear envelope breaks down.
Verified step by step guidance
1
Understand the stages of mitosis: Mitosis is divided into several phases: prophase, prometaphase, metaphase, anaphase, and telophase. Each phase has distinct events that occur.
Focus on prometaphase: Prometaphase is the stage following prophase and precedes metaphase. It is characterized by specific cellular changes.
Identify key events in prometaphase: During prometaphase, the nuclear envelope breaks down, allowing spindle fibers to interact with chromosomes.
Differentiate from other phases: Unlike metaphase where chromosomes align at the metaphase plate, or anaphase where sister chromatids separate, prometaphase is specifically marked by the breakdown of the nuclear envelope.
Review the options given: Compare the events listed in the problem with the key event of prometaphase. The correct answer is the breakdown of the nuclear envelope, as it is unique to prometaphase.