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Multiple Choice
Why is Duchenne Muscular Dystrophy almost never seen in girls?
A
It is an autosomal dominant disorder.
B
It is caused by a mutation on the Y chromosome.
C
It is an X-linked recessive disorder.
D
Girls have a higher resistance to genetic mutations.
Verified step by step guidance
1
Understand that Duchenne Muscular Dystrophy (DMD) is a genetic disorder that affects muscle function.
Recognize that DMD is an X-linked recessive disorder, meaning the gene causing the disorder is located on the X chromosome.
Recall that females have two X chromosomes (XX), while males have one X and one Y chromosome (XY).
In X-linked recessive disorders, a female would need to inherit two copies of the mutated gene (one from each parent) to express the disorder, which is less likely.
Males, having only one X chromosome, will express the disorder if they inherit the mutated gene from their mother, making DMD more common in boys.