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Multiple Choice
The phenotypes associated with Trisomy 21 include which of the following?
A
Tall stature and long limbs
B
Increased muscle tone and joint hypermobility
C
Intellectual disability and characteristic facial features
D
Progressive muscle weakness and respiratory issues
Verified step by step guidance
1
Understand the condition: Trisomy 21, also known as Down syndrome, is a genetic disorder caused by the presence of an extra chromosome 21.
Identify common phenotypes: Individuals with Trisomy 21 often exhibit intellectual disability and characteristic facial features, such as a flat facial profile, upward slanting eyes, and a small nose.
Recognize other associated features: While tall stature and long limbs, increased muscle tone, and joint hypermobility are not typical of Trisomy 21, individuals may have short stature and hypotonia (decreased muscle tone).
Differentiate from other conditions: Progressive muscle weakness and respiratory issues are more commonly associated with other genetic disorders, such as muscular dystrophy, rather than Trisomy 21.
Conclude with the correct phenotypes: Intellectual disability and characteristic facial features are the phenotypes most commonly associated with Trisomy 21.