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Multiple Choice
Which two hormones, produced by the thyroid and parathyroid glands, have antagonistic effects on blood calcium levels?
A
Insulin and glucagon
B
Thyroxine and triiodothyronine
C
Calcitonin and parathyroid hormone (PTH)
D
Aldosterone and cortisol
Verified step by step guidance
1
Step 1: Understand the role of the thyroid and parathyroid glands in regulating blood calcium levels. The thyroid gland produces calcitonin, which lowers blood calcium levels, while the parathyroid glands produce parathyroid hormone (PTH), which increases blood calcium levels.
Step 2: Learn the mechanism of calcitonin. Calcitonin reduces blood calcium levels by inhibiting osteoclast activity (cells that break down bone tissue) and promoting calcium deposition in bones. It also decreases calcium absorption in the intestines and increases calcium excretion in the kidneys.
Step 3: Learn the mechanism of parathyroid hormone (PTH). PTH increases blood calcium levels by stimulating osteoclast activity to release calcium from bones, enhancing calcium absorption in the intestines (via activation of vitamin D), and reducing calcium excretion in the kidneys.
Step 4: Recognize the antagonistic relationship between calcitonin and PTH. Calcitonin and PTH work in opposition to maintain calcium homeostasis in the blood. When blood calcium levels are high, calcitonin is released to lower them. When blood calcium levels are low, PTH is released to raise them.
Step 5: Eliminate incorrect options based on their functions. Insulin and glucagon regulate blood glucose, not calcium. Thyroxine and triiodothyronine are thyroid hormones involved in metabolism. Aldosterone and cortisol are adrenal hormones involved in fluid balance and stress response, respectively. The correct answer is calcitonin and parathyroid hormone (PTH).