Here are the essential concepts you must grasp in order to answer the question correctly.
Calcium Homeostasis
Calcium homeostasis refers to the regulation of calcium levels in the body, which is crucial for various physiological functions, including muscle contraction, nerve transmission, and blood coagulation. The body maintains calcium balance through a complex interplay of dietary intake, renal excretion, and hormonal regulation, ensuring that calcium levels remain within a narrow range.
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Introduction to Homeostasis
Hormonal Regulation
Hormonal regulation of calcium involves key hormones such as parathyroid hormone (PTH) and calcitonin, which work to increase or decrease blood calcium levels. PTH raises calcium levels by promoting bone resorption, increasing intestinal absorption, and reducing renal excretion, while calcitonin lowers calcium levels by inhibiting bone resorption and enhancing calcium excretion in the kidneys.
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Bone Reserves and Excretion
Bones serve as a major reservoir for calcium, releasing or absorbing calcium ions as needed to maintain homeostasis. The balance between calcium absorption from the gut, excretion through the kidneys, and mobilization from bone reserves is essential for maintaining stable blood calcium levels, highlighting the importance of both dietary intake and physiological regulation.
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