Skip to main content
Back

The Heart and Blood Vessels: Structure, Function, and Circulation

Study Guide - Smart Notes

Tailored notes based on your materials, expanded with key definitions, examples, and context.

Heart Anatomy and Location

Position and Landmarks

The heart is located obliquely to the midline within the mediastinum, between the lungs. It is anchored by the diaphragm and surrounded by the pericardium. Four anatomical 'corners' help identify its position: superior right, superior left, inferior right, and inferior left. The sternal angle and rib counting are used to locate these landmarks.

Heart location and mediastinum

Pericardium

The pericardium is a double-walled sac that encloses the heart, providing protection and anchorage. It consists of:

  • Fibrous pericardium: Anchors the heart to the diaphragm and great vessels.

  • Serous pericardium: Contains two layers (parietal and visceral/epicardium) with a pericardial cavity filled with fluid to reduce friction.

Pericardium and heart wall layers

External and Internal Anatomy of the Heart

External Features

The heart's surface features include grooves and vessels that help identify its chambers:

  • Coronary sulcus: Horizontal groove marking the boundary between atria and ventricles.

  • Anterior and posterior interventricular sulci: Vertical grooves indicating the interventricular septum.

  • Auricles and great vessels help identify the right and left atria and ventricles.

External anatomy of the heart

Internal Features

Key internal structures include:

  • Fossa ovalis: Remnant of the fetal foramen ovale.

  • Atrioventricular (AV) valves: Separate atria from ventricles (right: tricuspid, left: bicuspid/mitral).

  • Semilunar (SL) valves: Separate ventricles from arteries (right: pulmonary, left: aortic).

Internal anatomy of the heart Heart valves and internal features

Heart Valves and Their Function

Valve Structure and Function

Heart valves ensure unidirectional blood flow and prevent backflow:

  • Each valve has 2-3 cusps reinforced by endocardium.

  • Chordae tendineae connect AV valve cusps to papillary muscles, maintaining closure during ventricular contraction.

Valve anatomy and chordae tendineae

Coronary Circulation

The heart's own blood supply is provided by the coronary arteries and veins:

  • Left coronary artery (LCA) branches into the anterior interventricular artery (LAD) and circumflex artery (Cx).

  • Right coronary artery (RCA) branches into the marginal artery and posterior descending artery (PDA).

  • Venous return is via the coronary sinus, great, middle, and small cardiac veins.

Coronary arteries and veins

Heart Wall Structure

Layers of the Heart Wall

The heart wall consists of three layers:

  • Epicardium (visceral pericardium): Outer layer.

  • Myocardium: Middle muscular layer, composed of cardiac muscle tissue arranged in spiral and circular bundles. The connective tissue framework is called the cardiac skeleton.

  • Endocardium: Inner layer, continuous with the endothelium of blood vessels.

Heart wall layers and cardiac muscle bundles Cardiac muscle bundles

Blood Flow Through the Heart

Pathway of Blood

Blood flows through the heart in a specific sequence, ensuring oxygenation and systemic distribution:

  • Deoxygenated blood: SVC & IVC → Right atrium → Tricuspid valve → Right ventricle → Pulmonary valve → Pulmonary trunk (to lungs).

  • Oxygenated blood: Pulmonary veins → Left atrium → Mitral valve → Left ventricle → Aortic valve → Aorta (to body).

Blood flow through the heart

Valve Function During Cardiac Cycle

  • AV valves open during atrial systole/ventricular diastole; close during ventricular systole to prevent backflow.

  • Semilunar valves open during ventricular systole; close during ventricular diastole as blood fills the cusps.

Atrioventricular valve function Semilunar valve function

Auscultation Locations

Valve closures create characteristic heart sounds ('lub' for AV valves, 'dupp' for SL valves), best heard at specific chest locations.

Auscultation locations for heart valves

Electrical Conduction and Innervation of the Heart

Conduction System

About 1% of myocardial cells are autorhythmic, forming the heart's conduction system:

  • SA node (pacemaker) → AV nodeAV bundleBundle branchesSubendocardial conducting network (Purkinje fibers).

Electrical conduction system of the heart

Autonomic Innervation

The heart is innervated by both sympathetic and parasympathetic fibers:

  • Parasympathetic (vagus nerve): Decreases heart rate.

  • Sympathetic (cervical and thoracic chain ganglia): Increases heart rate and contraction strength.

Autonomic innervation of the heart

Blood Vessels: Structure and Circulation

Types and Structure of Blood Vessels

Blood vessels are classified as arteries, veins, or capillaries:

  • Arteries: Carry blood away from the heart.

  • Veins: Carry blood toward the heart.

  • Capillaries: Connect arteries and veins, allowing exchange of gases and nutrients.

  • Vessel walls have three layers: tunica intima, tunica media, and tunica adventitia.

Structure of arteries, veins, and capillaries

Pulmonary Circulation

Pulmonary circulation exchanges deoxygenated blood for oxygenated blood in the lungs:

  • Right ventricle → Pulmonary trunk → Pulmonary arteries → Lobar arteries → Arterioles → Capillaries (gas exchange) → Venules → Pulmonary veins → Left atrium.

Pulmonary circulation pathway

Systemic Circulation

Systemic circulation delivers oxygenated blood to the body and returns deoxygenated blood to the heart:

  • Left ventricle → Aorta → Elastic arteries → Muscular arteries → Arterioles → Capillaries (exchange) → Venules → Veins → Right atrium.

Systemic arteries Systemic veins

Pulse Points

Pulse points are locations where arteries are superficial and can be palpated to assess heart rate and blood flow.

Pulse points on the body

Great Vessels and Vascular Anastomoses

Great Vessels of the Heart

The aorta, superior and inferior vena cavae, and pulmonary arteries and veins are the major vessels entering and leaving the heart. The aortic arch gives rise to the brachiocephalic, left common carotid, and left subclavian arteries.

Great vessels of the heart

Anastomoses and Portal Systems

Anastomoses are connections between blood vessels that provide alternate routes for blood flow. Portal systems involve two capillary beds in series, such as the hepatic and renal portal systems.

Vascular anastomoses Hepatic portal system

Additional info: The notes above expand on the original content with definitions, context, and examples to ensure a comprehensive, self-contained study guide for college-level anatomy and physiology students.

Pearson Logo

Study Prep