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Ch. 10 Blood
Marieb - Essentials of Human Anatomy & Physiology 13th Edition
Marieb13th EditionEssentials of Human Anatomy & PhysiologyISBN: 9780135624340Not the one you use?Change textbook
All textbooksMarieb 13th EditionCh. 10 BloodProblem 13
Chapter 10, Problem 13

More than one choice may apply.
Place the letters of these events in the order they occur during hemostasis.

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1
Step 1: Identify the initial event in hemostasis, which is vascular spasm. This occurs immediately after the blood vessel is damaged, causing the vessel to constrict and reduce blood flow. In the images, this corresponds to image (d), where the vessel shows constriction indicated by arrows.
Step 2: Next, platelet plug formation occurs. Platelets adhere to the damaged site and aggregate to form a temporary plug. This is shown in image (c), where platelets are clustering at the injury site.
Step 3: Following platelet plug formation, coagulation or blood clotting takes place. This involves the conversion of fibrinogen to fibrin, which stabilizes the platelet plug by forming a mesh. Image (b) depicts this stage with the fibrin mesh forming inside the vessel.
Step 4: The final step is the repair and removal of the clot once the vessel is healed, but this is not shown in the images provided. The sequence of hemostasis events to order is therefore vascular spasm (d), platelet plug formation (c), and coagulation (b).
Step 5: To summarize, the correct order of events during hemostasis based on the images is: (d) vascular spasm, (c) platelet plug formation, and (b) coagulation.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Vascular Spasm

Vascular spasm is the immediate constriction of a damaged blood vessel to reduce blood flow and limit blood loss. This is the first response during hemostasis and helps minimize bleeding by narrowing the vessel at the injury site.
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Vascular Spasm

Platelet Plug Formation

Platelet plug formation involves platelets adhering to the exposed collagen fibers of the damaged vessel wall, becoming activated, and aggregating to form a temporary plug. This step is crucial for sealing small breaks in the vessel and preventing further blood loss.
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Platelet Plug Formation

Coagulation (Blood Clotting)

Coagulation is the process where fibrin threads form a mesh that stabilizes the platelet plug, creating a more durable blood clot. This involves a cascade of clotting factors that convert fibrinogen into fibrin, solidifying the clot and ensuring long-term vessel repair.
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Coagulation (Blood Clotting)
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