Multiple Choice
In eukaryotic cells, where does the Krebs (citric acid) cycle primarily occur?
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Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism
Citric Acid Cycle 1
Multiple Choice
In eukaryotic cells, where does the Krebs (citric acid) cycle primarily take place?
A
Inner mitochondrial membrane
B
Mitochondrial matrix
C
Cytosol
D
Nucleus
Verified step by step guidance1
Recall the main compartments of a eukaryotic cell relevant to energy metabolism: cytosol, mitochondrial matrix, inner mitochondrial membrane, and nucleus.
Understand that the Krebs cycle (citric acid cycle) is a series of enzymatic reactions that oxidize acetyl-CoA to produce NADH, FADH2, and ATP precursors.
Identify where the enzymes of the Krebs cycle are located. These enzymes are not embedded in membranes but are found in a specific aqueous environment inside mitochondria.
Recognize that the mitochondrial matrix is the fluid-filled space inside the inner membrane of mitochondria where the Krebs cycle enzymes reside and where the cycle takes place.
Conclude that the Krebs cycle primarily occurs in the mitochondrial matrix, not in the inner mitochondrial membrane, cytosol, or nucleus.
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