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Multiple Choice
What is the term used to describe an enzyme whose active site has lost its shape?
A
Allosteric
B
Denatured
C
Phosphorylated
D
Inhibited
Verified step by step guidance
1
Understand the concept of enzyme structure: Enzymes are proteins that catalyze biochemical reactions. Their active site is a specific region where substrates bind and reactions occur. The shape of the active site is crucial for enzyme function.
Learn about denaturation: Denaturation refers to the process where an enzyme loses its three-dimensional structure due to external factors such as heat, pH changes, or chemical agents. This loss of structure includes the active site, rendering the enzyme nonfunctional.
Differentiate between the terms provided: 'Allosteric' refers to enzymes regulated by molecules binding at sites other than the active site. 'Phosphorylated' describes enzymes modified by the addition of a phosphate group. 'Inhibited' refers to enzymes whose activity is reduced or stopped by inhibitors. None of these terms describe the loss of active site shape.
Recognize the correct term: The term 'denatured' specifically describes an enzyme whose active site has lost its shape due to structural changes, leading to a loss of function.
Apply this understanding to the question: Based on the explanation, the correct term for an enzyme whose active site has lost its shape is 'denatured'.