Multiple Choice
In oxidative phosphorylation, what is the relationship between the electron transport chain (ETC) and oxygen?
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Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation
Oxidative Phosphorylation 1
Multiple Choice
In oxidative phosphorylation during aerobic respiration, which enzyme complex directly catalyzes ATP synthesis using the proton motive force?
A
NADH dehydrogenase (Complex I)
B
Cytochrome oxidase (Complex IV)
C
Succinate dehydrogenase (Complex II)
D
ATP synthase (Complex V, -ATPase)
Verified step by step guidance1
Understand the role of each enzyme complex in the electron transport chain (ETC) during oxidative phosphorylation: Complex I (NADH dehydrogenase) transfers electrons from NADH to ubiquinone, pumping protons across the membrane.
Recognize that Complex II (Succinate dehydrogenase) transfers electrons from succinate to ubiquinone but does not pump protons, so it does not contribute directly to the proton motive force.
Know that Complex IV (Cytochrome c oxidase) transfers electrons to oxygen, the final electron acceptor, and pumps protons to help maintain the proton gradient.
Identify that the proton motive force generated by proton pumping across the inner mitochondrial membrane creates an electrochemical gradient used to drive ATP synthesis.
Recall that ATP synthase (Complex V, F\_0F\_1-ATPase) is the enzyme complex that directly uses the proton motive force to catalyze the synthesis of ATP from ADP and inorganic phosphate.
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