Multiple Choice
Which metabolic pathway primarily uses stored fat reserves (triacylglycerols) to generate ATP in cells?
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Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism
Fatty Acid Oxidation 1
Multiple Choice
In a resting skeletal muscle cell, most ATP is generated primarily by which metabolic process?
A
The pentose phosphate pathway generating NADPH for ATP synthesis
B
Anaerobic glycolysis producing lactate from glucose
C
ATP production exclusively from phosphocreatine (creatine phosphate) breakdown
D
Oxidative phosphorylation driven largely by mitochondrial -oxidation of fatty acids
Verified step by step guidance1
Understand the main metabolic pathways involved in ATP production in skeletal muscle cells: anaerobic glycolysis, phosphocreatine breakdown, pentose phosphate pathway, and oxidative phosphorylation.
Recognize that in resting skeletal muscle cells, energy demand is low and oxygen is readily available, favoring aerobic metabolism over anaerobic processes.
Recall that oxidative phosphorylation occurs in mitochondria and is the primary source of ATP during rest, utilizing substrates like fatty acids through \( \beta \)-oxidation.
Note that the pentose phosphate pathway mainly generates NADPH for biosynthetic reactions and does not directly produce ATP.
Conclude that the majority of ATP in resting skeletal muscle cells is generated by oxidative phosphorylation driven largely by mitochondrial \( \beta \)-oxidation of fatty acids.
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