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Multiple Choice
Which macromolecule provides the highest amount of energy per gram when metabolized in the human body?
A
Lipids
B
Carbohydrates
C
Nucleic acids
D
Proteins
Verified step by step guidance
1
Understand the concept of energy yield: When macromolecules are metabolized, they release energy that is measured in kilocalories per gram (kcal/g). Different macromolecules provide varying amounts of energy due to their chemical structure and the number of bonds available for oxidation.
Review the energy yield of each macromolecule: Lipids provide approximately 9 kcal/g, carbohydrates and proteins each provide about 4 kcal/g, and nucleic acids are not typically metabolized for energy in significant amounts in the human body.
Analyze why lipids provide the highest energy: Lipids have long hydrocarbon chains with many C-H bonds, which release a large amount of energy during oxidation. This makes them the most energy-dense macromolecule.
Consider the metabolic pathways: Lipids undergo beta-oxidation, which generates acetyl-CoA for entry into the citric acid cycle, producing a high yield of ATP. Carbohydrates are metabolized via glycolysis and the citric acid cycle, while proteins are broken down into amino acids and metabolized depending on their structure.
Conclude based on the comparison: Lipids provide the highest energy per gram due to their chemical composition and metabolic pathways, making them the most efficient energy source among the listed macromolecules.