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Multiple Choice
The proper three-dimensional shape and folding of a protein is assisted by _________.
A
ribosomes
B
molecular chaperones
C
phospholipids
D
DNA polymerases
Verified step by step guidance
1
Understand the concept of protein folding: Proteins are synthesized as linear chains of amino acids, but they must fold into specific three-dimensional shapes to become functional. This folding process is critical for their biological activity.
Learn about molecular chaperones: Molecular chaperones are specialized proteins that assist in the proper folding of other proteins. They prevent misfolding and aggregation, ensuring the protein achieves its correct structure.
Eliminate incorrect options: Ribosomes are involved in protein synthesis, not folding. Phospholipids are components of cell membranes and do not assist in protein folding. DNA polymerases are enzymes involved in DNA replication, unrelated to protein folding.
Recognize the correct answer: Molecular chaperones are the correct choice because they directly assist in the folding and stabilization of proteins during and after synthesis.
Connect the concept to broader biochemistry: Protein folding is essential for maintaining cellular function, and molecular chaperones play a key role in preventing diseases caused by misfolded proteins, such as Alzheimer's and Parkinson's.