Multiple Choice
In human cells, where does glycolysis primarily take place?
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Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway
Glycolysis 1
Multiple Choice
In glycolysis (conversion of one glucose molecule to two pyruvate molecules), what is the net yield of ATP per glucose under aerobic conditions (ignoring NADH shuttling differences)?
A
ATP net
B
ATP net
C
ATP net
D
ATP net
Verified step by step guidance1
Understand the overall process of glycolysis: one glucose molecule (6 carbons) is converted into two pyruvate molecules (3 carbons each).
Identify the ATP investment phase: glycolysis initially consumes 2 ATP molecules to phosphorylate glucose and its intermediates.
Identify the ATP payoff phase: glycolysis produces 4 ATP molecules through substrate-level phosphorylation when converting intermediates to pyruvate.
Calculate the net ATP yield by subtracting the ATP invested from the ATP produced: Net ATP = ATP produced - ATP consumed.
Conclude that the net ATP yield per glucose molecule in glycolysis under aerobic conditions (ignoring NADH shuttling) is 2 ATP.
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