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Multiple Choice
What happens to the coenzyme NAD$^+$ when it gains a hydrogen atom during a biochemical reaction?
A
It is reduced to NADH.
B
It is hydrolyzed to release ADP and ribose.
C
It forms a covalent bond with DNA.
D
It is oxidized to NADP$^+$.
Verified step by step guidance
1
Understand the role of NAD⁺ in biochemical reactions: NAD⁺ (nicotinamide adenine dinucleotide) is a coenzyme that acts as an electron carrier in redox reactions. It alternates between oxidized (NAD⁺) and reduced (NADH) states.
Recall the concept of reduction: Reduction is the gain of electrons or hydrogen atoms. When NAD⁺ gains a hydrogen atom, it is reduced to NADH.
Analyze the options provided: The correct answer must align with the biochemical function of NAD⁺. Reduction to NADH is consistent with its role as an electron carrier.
Eliminate incorrect options: Hydrolysis to release ADP and ribose is unrelated to NAD⁺'s function. Covalent bonding with DNA is not a typical role of NAD⁺. Oxidation to NADP⁺ is incorrect because NADP⁺ is a different coenzyme involved in anabolic reactions.
Conclude that the correct answer is: 'It is reduced to NADH,' as this matches the biochemical behavior of NAD⁺ when it gains a hydrogen atom.