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Multiple Choice
In skeletal muscle sarcomeres, which protein is the primary structural component of the thick filaments?
A
Actin
B
Troponin
C
Tropomyosin
D
Myosin (especially myosin II)
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1
Understand the structure of the sarcomere, which is the basic contractile unit of skeletal muscle. It consists of thick and thin filaments arranged in a highly organized manner.
Identify the proteins associated with the thin filaments: primarily actin, along with regulatory proteins troponin and tropomyosin.
Recognize that the thick filaments are mainly composed of myosin molecules, specifically myosin II in skeletal muscle.
Recall that myosin II has a tail region that forms the backbone of the thick filament and head regions that interact with actin to generate contraction.
Conclude that among the options given, myosin (especially myosin II) is the primary structural protein of the thick filaments in skeletal muscle sarcomeres.