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Multiple Choice
Which of the following best describes glycogenolysis?
A
The oxidation of fatty acids to produce ATP
B
The conversion of glucose to pyruvate
C
The breakdown of glycogen to glucose-1-phosphate and glucose
D
The synthesis of glycogen from glucose
Verified step by step guidance
1
Understand the term 'glycogenolysis': Glycogenolysis refers to the biochemical process where glycogen, a stored form of glucose in the liver and muscles, is broken down into glucose-1-phosphate and free glucose molecules to be used for energy.
Identify the key enzymes involved: Glycogenolysis is catalyzed by enzymes such as glycogen phosphorylase, which removes glucose units from glycogen, and debranching enzyme, which handles branch points in the glycogen structure.
Recognize the products of glycogenolysis: The primary product is glucose-1-phosphate, which can be converted into glucose-6-phosphate by the enzyme phosphoglucomutase. Glucose-6-phosphate can then enter glycolysis or be converted into free glucose in the liver for release into the bloodstream.
Differentiate glycogenolysis from other processes: Glycogenolysis is distinct from glycolysis (the breakdown of glucose to pyruvate), glycogenesis (the synthesis of glycogen from glucose), and fatty acid oxidation (the breakdown of fatty acids to produce ATP).
Match the description to the correct answer: Based on the definition and steps of glycogenolysis, the correct description is 'The breakdown of glycogen to glucose-1-phosphate and glucose.'