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Multiple Choice
Which of the following enzymes converts ATP to cAMP?
A
Phosphodiesterase
B
Hexokinase
C
Protein kinase A
D
Adenylate cyclase
Verified step by step guidance
1
Understand the role of ATP and cAMP in cellular signaling. ATP (adenosine triphosphate) is a molecule used for energy transfer, while cAMP (cyclic adenosine monophosphate) acts as a secondary messenger in signal transduction pathways.
Identify the enzyme responsible for converting ATP to cAMP. This process involves the removal of two phosphate groups from ATP and the formation of a cyclic structure in the remaining molecule.
Recall that adenylate cyclase is the enzyme that catalyzes this reaction. It is typically activated by G-protein-coupled receptors in response to extracellular signals.
Differentiate adenylate cyclase from other enzymes listed in the options. For example, phosphodiesterase breaks down cAMP into AMP, hexokinase phosphorylates glucose, and protein kinase A is activated by cAMP but does not produce it.
Conclude that adenylate cyclase is the correct enzyme responsible for converting ATP to cAMP, as it directly catalyzes this specific reaction in the signaling pathway.