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Multiple Choice
Which of the following is a direct result of glycolysis (per molecule of glucose) under aerobic conditions?
A
Generation of a proton gradient across the inner mitochondrial membrane to drive ATP synthase
B
Production of acetyl-CoA and release of
C
Net production of and
D
Net production of and (net) along with pyruvate
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Verified step by step guidance
1
Recall that glycolysis is the metabolic pathway that breaks down one molecule of glucose (6 carbons) into two molecules of pyruvate (3 carbons each).
Identify the direct products formed during glycolysis per glucose molecule: 2 pyruvate molecules, a net gain of 2 ATP molecules, and 2 NADH molecules.
Understand that glycolysis itself does not produce acetyl-CoA or release CO2; these occur later in the link reaction (pyruvate oxidation) after glycolysis.
Recognize that the generation of a proton gradient across the inner mitochondrial membrane is a result of the electron transport chain, which happens after glycolysis and the citric acid cycle, not during glycolysis itself.
Summarize that the direct result of glycolysis under aerobic conditions is the net production of 2 ATP, 2 NADH, and 2 pyruvate molecules per glucose molecule.