Multiple Choice
In mammalian liver, which compound is a major byproduct of amino acid catabolism due to detoxification of released ammonia?
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Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation
Amino Acid Oxidation 1
Multiple Choice
Which B vitamin is most directly required as a coenzyme for many amino acid metabolism reactions, especially transamination?
A
Vitamin (niacin; /)
B
Vitamin (pyridoxine; pyridoxal phosphate, PLP)
C
Vitamin (cobalamin)
D
Vitamin (thiamine; thiamine pyrophosphate, TPP)
Verified step by step guidance1
Understand that the question asks which B vitamin acts as a coenzyme specifically in amino acid metabolism, focusing on transamination reactions.
Recall that transamination involves the transfer of an amino group from an amino acid to a keto acid, a key step in amino acid catabolism and synthesis.
Identify the coenzyme that facilitates this amino group transfer; this coenzyme is a derivative of a B vitamin and is essential for the function of aminotransferase enzymes.
Recognize that pyridoxal phosphate (PLP), the active form of Vitamin B6 (pyridoxine), serves as the coenzyme in these transamination reactions.
Conclude that Vitamin B6 is the B vitamin most directly required as a coenzyme for many amino acid metabolism reactions, especially transamination.
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