Multiple Choice
Which of the following would be unlikely to contribute to the substrate specificity of an enzyme?
19
views
7. Enzyme Inhibition and Regulation
Enzyme Inhibition
Struggling with Biochemistry?
Join thousands of students who trust us to help them ace their exams!Watch the first videoMultiple Choice
Which type of enzyme inhibitor binds to the active site of the enzyme, competing directly with the substrate?
A
Competitive inhibitor
B
Noncompetitive inhibitor
C
Uncompetitive inhibitor
Verified step by step guidance1
Understand the concept of enzyme inhibition: Enzyme inhibitors are molecules that reduce the activity of enzymes by interfering with their ability to bind substrates or catalyze reactions.
Learn about competitive inhibition: A competitive inhibitor resembles the substrate and binds directly to the active site of the enzyme, preventing the substrate from binding. This type of inhibition is reversible and depends on the concentration of the inhibitor and substrate.
Compare competitive inhibition with other types: Noncompetitive inhibitors bind to a site other than the active site, altering the enzyme's shape and function, while uncompetitive inhibitors bind only to the enzyme-substrate complex, stabilizing it and preventing product formation.
Visualize the mechanism: In competitive inhibition, the inhibitor and substrate compete for the same active site. If the inhibitor concentration is high, it reduces the likelihood of substrate binding, thereby decreasing enzyme activity.
Relate to experimental observations: Competitive inhibition can be identified by studying enzyme kinetics. In a Lineweaver-Burk plot, competitive inhibitors increase the apparent Km (Michaelis constant) without affecting Vmax (maximum reaction velocity).
Related Videos
Related Practice
Enzyme Inhibition practice set
Problem sets built by lead tutorsExpert video explanations