Multiple Choice
Which of the following best distinguishes covalent catalysis from acid-base catalysis in enzyme mechanisms?
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7. Enzyme Inhibition and Regulation
Enzyme Inhibition
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Join thousands of students who trust us to help them ace their exams!Watch the first videoMultiple Choice
The synthesis of a repressible enzyme is inhibited by which of the following?
A
The end product of the metabolic pathway
B
A coenzyme
C
The substrate of the enzyme
D
A competitive inhibitor
Verified step by step guidance1
Understand the concept of a repressible enzyme: A repressible enzyme is part of a metabolic pathway where its synthesis is regulated by feedback inhibition. This means the production of the enzyme is controlled by the presence or absence of certain molecules.
Identify the role of the end product in feedback inhibition: In a repressible system, the end product of the metabolic pathway often acts as a signal to stop the synthesis of the enzyme. This is a form of negative feedback regulation.
Analyze the options provided: A coenzyme, the substrate of the enzyme, and a competitive inhibitor do not directly inhibit the synthesis of a repressible enzyme. Instead, these molecules typically affect enzyme activity or function, not its production.
Relate the correct answer to the metabolic pathway: The end product of the pathway accumulates and binds to a regulatory protein or directly to the DNA, preventing transcription of the enzyme's gene. This ensures that the enzyme is not synthesized when the end product is abundant.
Conclude that the correct answer is 'The end product of the metabolic pathway,' as it directly inhibits the synthesis of the repressible enzyme through feedback regulation.
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