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Multiple Choice
For each turn of the citric acid cycle per acetyl-CoA oxidized, how many molecules of NADH are produced?
A
3 NADH
B
4 NADH
C
2 NADH
D
6 NADH
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Verified step by step guidance
1
Recall that the citric acid cycle (also known as the Krebs cycle or TCA cycle) processes one acetyl-CoA molecule per turn.
Identify the key steps in the cycle where NADH is produced: these occur during the oxidation of isocitrate to α-ketoglutarate, α-ketoglutarate to succinyl-CoA, and malate to oxaloacetate.
Count the number of NADH molecules generated at these steps, noting that each step produces one NADH molecule.
Sum the NADH molecules produced in these three steps to find the total NADH produced per acetyl-CoA oxidized.
Conclude that the total number of NADH molecules produced per turn of the citric acid cycle is the sum from step 4.