Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

3. Amino Acids

Amino Acid Groups

Biochemistry

3. Amino Acids

Amino Acid Groups

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Multiple Choice

When an aminoacyl-tRNA synthetase charges a tRNA, which of the following occurs?

The tRNA is hydrolyzed to release free nucleotides.

A peptide bond is formed between two amino acids.

An amino acid is covalently attached to the 3' end of the tRNA.

The anticodon of the tRNA is modified to match the mRNA codon.

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Verified step by step guidance

Step 1: Understand the role of aminoacyl-tRNA synthetase. This enzyme is responsible for attaching the correct amino acid to its corresponding tRNA molecule, a process known as 'charging' the tRNA.

Step 2: Recall the structure of tRNA. tRNA has a 3' end where the amino acid is covalently attached during the charging process. This attachment occurs via an ester bond between the carboxyl group of the amino acid and the hydroxyl group of the ribose sugar at the 3' end of the tRNA.

Step 3: Note that the anticodon region of the tRNA, which pairs with the mRNA codon during translation, is not modified during the charging process. The anticodon remains unchanged and specific to the mRNA codon it will recognize.

Step 4: Eliminate incorrect options. The tRNA is not hydrolyzed to release free nucleotides, nor is a peptide bond formed between amino acids during this step. Peptide bond formation occurs later during translation in the ribosome.

Step 5: Conclude that the correct process during tRNA charging is the covalent attachment of an amino acid to the 3' end of the tRNA by aminoacyl-tRNA synthetase.