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Multiple Choice
Which of the following statements about amino acid-based hormones is correct?
A
Most amino acid-based hormones are water soluble and cannot cross the plasma membrane.
B
All amino acid-based hormones are lipid soluble and can cross the plasma membrane.
C
Amino acid-based hormones are always derived from cholesterol.
D
Amino acid-based hormones bind to intracellular receptors.
Verified step by step guidance
1
Step 1: Understand the nature of amino acid-based hormones. Amino acid-based hormones are typically derived from amino acids and include peptides, proteins, and amines. They are generally water-soluble, meaning they dissolve in water and cannot easily pass through the lipid bilayer of the plasma membrane.
Step 2: Analyze the solubility and mechanism of action of amino acid-based hormones. Since they are water-soluble, they cannot cross the plasma membrane directly. Instead, they bind to receptors on the cell surface, triggering a signaling cascade inside the cell.
Step 3: Eliminate incorrect options. For example, the statement 'All amino acid-based hormones are lipid soluble and can cross the plasma membrane' is incorrect because most amino acid-based hormones are water-soluble. Similarly, 'Amino acid-based hormones are always derived from cholesterol' is incorrect because cholesterol is the precursor for steroid hormones, not amino acid-based hormones.
Step 4: Evaluate the statement 'Amino acid-based hormones bind to intracellular receptors.' This is incorrect because amino acid-based hormones typically bind to extracellular receptors on the plasma membrane due to their inability to cross the membrane.
Step 5: Confirm the correct statement. The correct answer is 'Most amino acid-based hormones are water soluble and cannot cross the plasma membrane,' as this aligns with the biochemical properties and mechanism of action of these hormones.