Multiple Choice
In eukaryotic cells, where is ATP synthase (Complex V) located during oxidative phosphorylation?
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Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation
Oxidative Phosphorylation 3
Multiple Choice
In oxidative phosphorylation, what is the primary function of ATP synthase?
A
It uses the proton-motive force to synthesize ATP from ADP and inorganic phosphate (Pi).
B
It pumps protons from the intermembrane space into the mitochondrial matrix to create the proton gradient.
C
It catalyzes the reduction of to at the end of the electron transport chain.
D
It transfers electrons from NADH to ubiquinone (coenzyme Q).
Verified step by step guidance1
Understand that ATP synthase is an enzyme complex located in the inner mitochondrial membrane responsible for ATP production during oxidative phosphorylation.
Recognize that the electron transport chain creates a proton gradient (proton-motive force) by pumping protons from the mitochondrial matrix to the intermembrane space.
Know that ATP synthase uses this proton gradient to drive the synthesis of ATP by allowing protons to flow back into the mitochondrial matrix through its channel.
Recall the chemical reaction catalyzed by ATP synthase: \(\mathrm{ADP} + \mathrm{P_i} + \text{proton-motive force} \rightarrow \mathrm{ATP} + \mathrm{H_2O}\), where \(\mathrm{P_i}\) is inorganic phosphate.
Distinguish ATP synthase's function from other components of oxidative phosphorylation, such as proton pumping (done by complexes I, III, IV), oxygen reduction (complex IV), and electron transfer (complex I and others).
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