In the lungs, the _________ pressure of CO 2 causes hemoglobin to _________ CO 2 and H + . The _________ pressure of O 2 causes O 2 to _________ hemoglobin, allowing for its transportation to the tissues.

Alright. So this practice problem just wants us to fill in these blanks with one of these 6 potential answer options below. And so the sentences say that in the lungs, the blank pressure of c 02 causes hemoglobin to blank c02 and h plus and the blank pressure of oxygen gas causes oxygen gas to blank hemoglobin allowing for its transportation to the tissues. And so what we need to recall is that in the lungs there's going to be constant inhalation and exhalation. And so with every single breath, we're going to exhale lots and lots of c o two. And if we exhale c o two, that means that we're going to have very, very low partial pressure of CO 2 in the lungs. And so the very first blank we know needs to have the word 'low' in it. And so we can eliminate any answer option that suggests high, for this first blank. So, we can eliminate option B, option C, and option E. Now, of course, if there's very low partial pressure of CO2, it's going to be so low that hemoglobin is gonna be forced to release its c02. And, when it releases its c02, that's also gonna cause the hydrogen ions that it's bound to to be released as well. And so this second blank we want to say released and so we can eliminate answer options that suggest, it's going to bind c o two and h plus in the lungs. And so we can eliminate answer option a for that reason. So, now, we're between either option d or option f and so, moving on to the next blank, it says, the blank pressure of oxygen and so, we know that in the lungs, we're gonna be constantly inhaling oxygen and so if we're inhaling oxygen, there's going to be a high concentration or high partial pressure of oxygen. And so here we want this to say high. And so the 3rd blank we want to say high and so notice option d says high, but option f says, low. And so option f is gonna be incorrect. And that must mean that option d here is the correct answer. And so, to fill out the rest of this, blank, it says that the high pressure of oxygen causes oxygen to bind hemoglobin. So we can write in bind here, allowing for its transportation to the tissues, allowing for oxygen to be transported to the tissues. And so, it's true that option d here is the correct answer and that concludes this practice. So I'll see you guys in our next

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8. Protein Function

Hemoglobin Binding in Tissues & Lungs

Biochemistry

8. Protein Function

Hemoglobin Binding in Tissues & Lungs

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Multiple Choice

In the lungs, the _____ pressure of CO₂ causes hemoglobin to _ CO₂ and H⁺. The _ pressure of O₂ causes O₂ to _____ hemoglobin, allowing for its transportation to the tissues.

Low; Bind; Low; Release.

High; Bind; Low; Release.

High; Bind; High; Release.

Low; Release; High; Bind.

High; Release; Low; Bind.

Low; Release; Low; Bind. Blood pH in Tissues ≈ 7.2 Blood pH in Lungs ≈ 7.6 Blood pH ≈ 7.4

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Verified step by step guidance

Understand the role of hemoglobin in gas exchange: Hemoglobin is a protein in red blood cells that carries oxygen from the lungs to the tissues and helps transport carbon dioxide back to the lungs.

Consider the effect of partial pressures: In the lungs, the partial pressure of oxygen is high, which promotes the binding of oxygen to hemoglobin. Conversely, the partial pressure of carbon dioxide is low, which facilitates the release of CO2 and H+ from hemoglobin.

Analyze the Bohr effect: The Bohr effect describes how changes in blood pH and CO2 concentration affect hemoglobin's affinity for oxygen. In the lungs, a higher pH (around 7.6) increases hemoglobin's affinity for oxygen, promoting oxygen binding.

Apply the concept to the given options: The correct sequence involves low CO2 pressure leading to the release of CO2 and H+, and high O2 pressure leading to the binding of O2 to hemoglobin.

Relate blood pH to hemoglobin function: In tissues, the blood pH is lower (around 7.2), which facilitates the release of oxygen from hemoglobin due to the Bohr effect, while in the lungs, the higher pH (around 7.6) enhances oxygen binding.