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Multiple Choice
Which of the following correctly sequences the major steps of endochondral ossification?
A
Cartilage model develops → periosteal bone collar forms → secondary ossification centers develop → cartilage calcifies → primary ossification center develops
B
Cartilage calcifies → cartilage model develops → periosteal bone collar forms → secondary ossification centers develop → primary ossification center develops
C
Cartilage model develops → cartilage calcifies → periosteal bone collar forms → primary ossification center develops → secondary ossification centers develop
D
Primary ossification center develops → cartilage model develops → cartilage calcifies → periosteal bone collar forms → secondary ossification centers develop
Verified step by step guidance
1
Understand the concept of endochondral ossification: It is the process by which bone tissue is formed from a cartilage model, primarily occurring in long bones during development.
Identify the major steps involved in endochondral ossification: These include the development of a cartilage model, calcification of cartilage, formation of a periosteal bone collar, development of a primary ossification center, and formation of secondary ossification centers.
Sequence the steps logically: The process begins with the cartilage model developing, followed by the calcification of cartilage. Next, the periosteal bone collar forms around the cartilage model. The primary ossification center then develops in the diaphysis (shaft of the bone), and finally, secondary ossification centers form in the epiphyses (ends of the bone).
Compare the provided sequences: Analyze each sequence to determine which one matches the correct order of steps in endochondral ossification.
Select the correct sequence: Based on the logical progression of steps, the correct sequence is 'Cartilage model develops → cartilage calcifies → periosteal bone collar forms → primary ossification center develops → secondary ossification centers develop.'