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Multiple Choice
During which phase of mitosis do the nuclear envelope and nucleoli disappear?
A
Metaphase
B
Anaphase
C
Telophase
D
Prophase
Verified step by step guidance
1
Understand the stages of mitosis: Mitosis is divided into several phases: prophase, metaphase, anaphase, and telophase. Each phase has distinct events that occur within the cell.
Focus on prophase: During prophase, several key changes occur in the cell. The chromatin condenses into visible chromosomes, and the mitotic spindle begins to form.
Identify the disappearance of the nuclear envelope and nucleoli: In prophase, the nuclear envelope breaks down, and the nucleoli disappear, allowing the chromosomes to be accessible for the spindle fibers.
Compare with other phases: In metaphase, chromosomes align at the cell's equatorial plane. In anaphase, sister chromatids are pulled apart. In telophase, the nuclear envelope reforms around the separated chromosomes.
Conclude that prophase is the phase where the nuclear envelope and nucleoli disappear, setting the stage for chromosome alignment and separation in subsequent phases.