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Multiple Choice
Which of the following cell signaling molecules crosses the cell membrane the easiest?
A
Peptide hormones
B
Steroid hormones
C
Neurotransmitters
D
Cytokines
Verified step by step guidance
1
Understand the nature of the cell membrane: The cell membrane is primarily composed of a phospholipid bilayer, which is hydrophobic in nature. This means that molecules that are nonpolar and lipid-soluble can pass through more easily than polar or charged molecules.
Identify the characteristics of each signaling molecule: Peptide hormones are generally large and polar, making them less likely to pass through the lipid bilayer without assistance. Neurotransmitters can vary, but many are charged or polar. Cytokines are typically proteins, which are large and polar.
Consider the properties of steroid hormones: Steroid hormones are derived from cholesterol, making them nonpolar and lipid-soluble. This allows them to easily diffuse through the lipid bilayer of the cell membrane without the need for transport proteins.
Compare the ability of each molecule to cross the cell membrane: Given their nonpolar and lipid-soluble nature, steroid hormones can cross the cell membrane more easily than peptide hormones, neurotransmitters, or cytokines.
Conclude that steroid hormones are the signaling molecules that cross the cell membrane the easiest due to their lipid-soluble nature, allowing them to diffuse directly through the hydrophobic core of the phospholipid bilayer.