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Multiple Choice
During which phase of mitosis are sister chromatids connected to each other at the centromere?
A
Anaphase
B
Prophase
C
Telophase
D
Metaphase
Verified step by step guidance
1
Understand the process of mitosis, which is the division of a single cell into two genetically identical daughter cells. Mitosis consists of several phases: prophase, metaphase, anaphase, and telophase.
In prophase, the chromatin condenses into visible chromosomes, and each chromosome consists of two sister chromatids connected at a region called the centromere.
During metaphase, the chromosomes align at the cell's equatorial plane, known as the metaphase plate. The sister chromatids are still connected at the centromere during this phase.
In anaphase, the centromeres split, and the sister chromatids are pulled apart toward opposite poles of the cell by the spindle fibers.
In telophase, the separated chromatids, now individual chromosomes, reach the poles of the cell, and the nuclear envelope begins to reform around each set of chromosomes.