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Multiple Choice
What is the role of single-strand binding proteins (SSBs) in DNA replication?
A
They prevent the re-annealing of DNA strands.
B
They synthesize new DNA strands.
C
They unwind the DNA double helix.
D
They join Okazaki fragments together.
Verified step by step guidance
1
Understand the process of DNA replication: DNA replication is the process by which a cell duplicates its DNA, ensuring that each daughter cell receives an identical copy of the genetic material.
Identify the role of single-strand binding proteins (SSBs): During DNA replication, the double-stranded DNA is unwound to form two single strands. SSBs bind to these single strands to stabilize them and prevent them from re-annealing or forming secondary structures.
Clarify why preventing re-annealing is important: If the single strands were to re-anneal or form secondary structures, it would hinder the replication process, as the DNA polymerase would not be able to access the template strand effectively.
Differentiate SSBs from other proteins involved in replication: SSBs do not synthesize new DNA strands, unwind the DNA double helix, or join Okazaki fragments. These functions are performed by DNA polymerase, helicase, and DNA ligase, respectively.
Summarize the role of SSBs: Single-strand binding proteins are crucial for maintaining the integrity of the single-stranded DNA during replication, ensuring that the replication machinery can efficiently synthesize new DNA strands.