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Multiple Choice
Which of the following is a similarity between breast cancer and colorectal cancer?
A
Both originate exclusively in glandular tissue.
B
Both can involve mutations in the BRCA1 gene.
C
Both are more common in males than females.
D
Both may be influenced by inherited genetic mutations.
Verified step by step guidance
1
Understand the question: The problem asks for a similarity between breast cancer and colorectal cancer, focusing on genetic and biological factors.
Review the options provided: Analyze each statement to determine its accuracy and relevance to both breast and colorectal cancer.
Option 1: 'Both originate exclusively in glandular tissue.' - This is incorrect because while breast cancer often originates in glandular tissue (lobules or ducts), colorectal cancer originates in the lining of the colon or rectum, which is not exclusively glandular.
Option 2: 'Both can involve mutations in the BRCA1 gene.' - This is incorrect because BRCA1 mutations are strongly associated with breast and ovarian cancers, but they are not commonly linked to colorectal cancer.
Option 4: 'Both may be influenced by inherited genetic mutations.' - This is correct because both breast and colorectal cancers can be influenced by inherited genetic mutations, such as mutations in the BRCA1/BRCA2 genes for breast cancer and mutations in genes like APC or MLH1 for colorectal cancer.