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Multiple Choice
What is the inheritance pattern of the disorder shown in the pedigree?
A
X-linked dominant
B
Autosomal recessive
C
Autosomal dominant
D
Mitochondrial
Verified step by step guidance
1
Examine the pedigree chart to identify the pattern of inheritance. Look for key indicators such as whether the disorder appears in every generation, which can suggest a dominant inheritance pattern.
Determine if both males and females are affected equally. In autosomal dominant inheritance, both genders are typically affected equally, whereas X-linked patterns often show gender bias.
Check if the disorder is passed from affected parents to their children. In autosomal dominant inheritance, an affected individual has a 50% chance of passing the disorder to each child.
Look for instances where unaffected parents have affected children. If this occurs, it suggests a recessive pattern, which is not the case for autosomal dominant inheritance.
Consider if the disorder is passed from mother to all children, which would suggest mitochondrial inheritance. If this pattern is not observed, it supports the autosomal dominant conclusion.