Multiple Choice
Are the alleles on a recombinant chromatid the same as those on the original chromatid?
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12. Meiosis
Genes & Alleles
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Which of the following do you expect if an individual is heterozygous for the sickle-cell trait?
A
The individual will have normal hemoglobin and no symptoms of sickle-cell disease.
B
The individual will have severe sickle-cell disease symptoms.
C
The individual will have no sickle-shaped cells and will be a carrier without any symptoms.
D
The individual will have some sickle-shaped red blood cells but generally mild symptoms.
Verified step by step guidance1
Understand the genetic basis of the sickle-cell trait: It is caused by a mutation in the hemoglobin gene. Individuals with one normal allele and one mutated allele are heterozygous.
Recognize that heterozygous individuals have both normal and abnormal hemoglobin. This results in a mixture of normal and sickle-shaped red blood cells.
Consider the symptoms: Heterozygous individuals typically have mild symptoms or are asymptomatic because they have enough normal hemoglobin to prevent severe symptoms.
Identify the role of carriers: Heterozygous individuals are carriers of the sickle-cell trait, meaning they can pass the mutated gene to their offspring.
Conclude that the presence of some sickle-shaped cells in heterozygous individuals leads to generally mild symptoms, not severe disease.
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