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Multiple Choice
Cancer is not usually inherited because:
A
cancer cells cannot survive outside the original host
B
cancer is always caused by environmental factors only
C
all cancer-causing genes are eliminated during meiosis
D
most cancers are caused by somatic mutations that are not passed to offspring
Verified step by step guidance
1
Understand the difference between somatic and germline mutations: Somatic mutations occur in non-reproductive cells and are not passed to offspring, while germline mutations occur in reproductive cells and can be inherited.
Recognize that cancer is typically caused by somatic mutations, which arise in specific cells during an individual's lifetime due to factors like DNA replication errors, environmental exposures, or other cellular processes.
Note that somatic mutations are confined to the individual in which they occur and do not affect the DNA of reproductive cells (sperm or egg). Therefore, they cannot be transmitted to the next generation.
Eliminate the incorrect options: Cancer cells can survive outside the host in laboratory conditions, cancer is not always caused by environmental factors (genetic predispositions can play a role), and cancer-causing genes are not eliminated during meiosis.
Conclude that the correct answer is: 'Most cancers are caused by somatic mutations that are not passed to offspring,' as these mutations are not present in the germline cells responsible for inheritance.