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Multiple Choice
Which event occurs during eukaryotic translation termination?
A
The initiator tRNA binds to the start codon.
B
A peptide bond forms between two amino acids.
C
The small ribosomal subunit attaches to the mRNA.
D
A release factor binds to the stop codon in the A site of the ribosome.
Verified step by step guidance
1
Understand the process of translation termination in eukaryotes: Translation termination occurs when the ribosome encounters a stop codon (UAA, UAG, or UGA) on the mRNA strand during protein synthesis.
Recognize the role of release factors: Release factors are specialized proteins that bind to the stop codon in the A site of the ribosome, signaling the end of translation.
Identify the mechanism of action: When the release factor binds to the stop codon, it triggers the hydrolysis of the bond between the polypeptide chain and the tRNA in the P site, releasing the newly synthesized protein.
Understand ribosome disassembly: After the polypeptide is released, the ribosome subunits (small and large) detach from the mRNA and dissociate, allowing them to be reused for another round of translation.
Review the incorrect options: The initiator tRNA binding to the start codon, peptide bond formation, and small ribosomal subunit attachment to mRNA are events that occur during earlier stages of translation (initiation and elongation), not termination.