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Multiple Choice
Which of the following is directly involved in the initiation of translation in eukaryotic cells?
A
Ribosomal small subunit
B
Initiator tRNA carrying methionine
C
RNA primase
D
DNA polymerase
Verified step by step guidance
1
Understand the process of translation initiation in eukaryotic cells: Translation is the process by which ribosomes synthesize proteins using mRNA as a template. The initiation phase involves assembling the components required to start protein synthesis.
Identify the key components involved in translation initiation: These include the ribosomal small subunit, the initiator tRNA carrying methionine, the mRNA strand, and various initiation factors.
Focus on the role of the initiator tRNA: In eukaryotic cells, the initiator tRNA carries methionine (Met) and is specifically charged with this amino acid. It recognizes the start codon (AUG) on the mRNA and pairs with it to establish the starting point for translation.
Understand the role of the ribosomal small subunit: The ribosomal small subunit binds to the mRNA and scans for the start codon (AUG). Once the start codon is located, the initiator tRNA carrying methionine binds to it, forming the initiation complex.
Eliminate incorrect options: RNA primase and DNA polymerase are enzymes involved in DNA replication, not translation. Therefore, they are not directly involved in the initiation of translation in eukaryotic cells.