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Multiple Choice
Which type of mutation stops the translation of the mRNA?
A
Frameshift mutation
B
Nonsense mutation
C
Silent mutation
D
Missense mutation
Verified step by step guidance
1
Understand the types of mutations: A mutation is a change in the nucleotide sequence of DNA. Different types of mutations can affect protein synthesis in various ways.
Learn about nonsense mutations: A nonsense mutation is a type of mutation where a codon that codes for an amino acid is changed to a stop codon. This results in premature termination of protein synthesis.
Explore the impact of nonsense mutations: When a nonsense mutation occurs, the ribosome stops translation prematurely, leading to a truncated and usually nonfunctional protein.
Differentiate nonsense mutations from other types: Frameshift mutations involve insertion or deletion of nucleotides, altering the reading frame. Silent mutations do not change the amino acid sequence, and missense mutations result in a different amino acid.
Identify the correct mutation type: Based on the definition and impact, nonsense mutations are the ones that stop the translation of mRNA by introducing a stop codon.