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Multiple Choice
Which of the following enzymes creates a primer for DNA polymerase during DNA replication?
A
Helicase
B
Topoisomerase
C
Ligase
D
Primase
Verified step by step guidance
1
Understand the role of each enzyme listed in the options: Helicase unwinds the DNA double helix, Topoisomerase relieves the tension created by unwinding, and Ligase joins Okazaki fragments on the lagging strand.
Recognize that DNA polymerase requires a primer to initiate DNA synthesis. This primer is a short RNA sequence.
Identify the enzyme responsible for synthesizing the RNA primer. This enzyme is known as Primase.
Primase synthesizes a short RNA primer complementary to the DNA template strand, providing a starting point for DNA polymerase to begin adding DNA nucleotides.
Conclude that Primase is the enzyme that creates the primer necessary for DNA polymerase to function during DNA replication.