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Multiple Choice
What are the base-pairing rules for DNA according to Chargaff's Rules?
A
A pairs with G, and C pairs with T
B
A pairs with T, and C pairs with G
C
A pairs with A, and C pairs with C
D
A pairs with C, and G pairs with T
Verified step by step guidance
1
Understand that Chargaff's Rules are based on the observation that in DNA, the amount of adenine (A) is equal to thymine (T), and the amount of cytosine (C) is equal to guanine (G). This is due to the base-pairing nature of DNA.
Recognize that DNA is composed of two strands forming a double helix, where the bases on one strand pair with the bases on the opposite strand.
Identify the correct base-pairing: Adenine (A) pairs with Thymine (T) through two hydrogen bonds, and Cytosine (C) pairs with Guanine (G) through three hydrogen bonds.
Eliminate incorrect options by checking if they violate the base-pairing rules: A cannot pair with G, C cannot pair with T, A cannot pair with A, and C cannot pair with C.
Conclude that the correct base-pairing according to Chargaff's Rules is: A pairs with T, and C pairs with G.