Join thousands of students who trust us to help them ace their exams!Watch the first video
Multiple Choice
Which ion diffuses into the synaptic knob to trigger the release of neurotransmitters during synaptic transmission?
A
Potassium ions ($\mathrm{K^+}$)
B
Calcium ions ($\mathrm{Ca^{2+}}$)
C
Chloride ions ($\mathrm{Cl^-}$)
D
Sodium ions ($\mathrm{Na^+}$)
Verified step by step guidance
1
Understand the context of synaptic transmission: Synaptic transmission is the process by which neurons communicate with each other or with target cells, such as muscle cells, through the release of neurotransmitters.
Identify the role of ions in synaptic transmission: During synaptic transmission, specific ions play a critical role in triggering the release of neurotransmitters from the synaptic knob (axon terminal).
Focus on calcium ions ($\mathrm{Ca^{2+}}$): When an action potential reaches the synaptic knob, voltage-gated calcium channels open, allowing calcium ions ($\mathrm{Ca^{2+}}$) to diffuse into the synaptic knob.
Explain the mechanism: The influx of calcium ions ($\mathrm{Ca^{2+}}$) triggers the fusion of synaptic vesicles containing neurotransmitters with the presynaptic membrane, leading to the release of neurotransmitters into the synaptic cleft.
Clarify why other ions are not correct: Potassium ions ($\mathrm{K^+}$), chloride ions ($\mathrm{Cl^-}$), and sodium ions ($\mathrm{Na^+}$) have roles in other aspects of neuronal function, such as maintaining resting membrane potential or propagating action potentials, but they do not directly trigger neurotransmitter release during synaptic transmission.