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Multiple Choice
Which of the following are similarities between DNA polymerase and RNA polymerase?
A
Both enzymes can proofread and correct errors during synthesis.
B
Both enzymes synthesize nucleic acids in the 5' to 3' direction.
C
Both enzymes require a primer to initiate synthesis.
D
Both enzymes are involved in the replication of DNA.
Verified step by step guidance
1
Understand the roles of DNA polymerase and RNA polymerase: DNA polymerase is involved in DNA replication, while RNA polymerase is involved in transcription, synthesizing RNA from a DNA template.
Identify the direction of synthesis: Both DNA polymerase and RNA polymerase synthesize nucleic acids in the 5' to 3' direction. This means they add nucleotides to the 3' end of the growing chain.
Consider the need for a primer: DNA polymerase requires a primer to initiate synthesis, as it cannot start a new strand on its own. RNA polymerase, however, does not require a primer and can start synthesizing RNA directly from the DNA template.
Evaluate proofreading capabilities: DNA polymerase has proofreading abilities to correct errors during DNA replication. RNA polymerase, on the other hand, generally lacks this proofreading function, leading to a higher error rate in RNA synthesis.
Clarify involvement in DNA replication: DNA polymerase is directly involved in DNA replication, while RNA polymerase is not. RNA polymerase is involved in transcription, which is the process of making RNA from a DNA template, not replicating DNA.