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Multiple Choice
Which of the following mechanisms help to explain how changes to the cell cycle can lead to cancer?
A
Decreased cell proliferation
B
Increased apoptosis
C
Enhanced DNA repair mechanisms
D
Mutations in tumor suppressor genes
Verified step by step guidance
1
Understand the cell cycle: The cell cycle is a series of phases that cells go through to grow and divide. It includes phases such as G1, S, G2, and M. Proper regulation of the cell cycle is crucial for normal cell function and prevention of uncontrolled cell growth.
Learn about tumor suppressor genes: Tumor suppressor genes are a type of gene that helps regulate the cell cycle and prevent cells from dividing too quickly or in an uncontrolled way. They act as a brake on cell proliferation.
Recognize the role of mutations: Mutations in tumor suppressor genes can lead to a loss of function. This means that the 'brake' on cell division is removed, allowing cells to proliferate uncontrollably, which can lead to cancer.
Differentiate between mechanisms: Decreased cell proliferation, increased apoptosis, and enhanced DNA repair mechanisms are generally protective against cancer. In contrast, mutations in tumor suppressor genes can lead to cancer by allowing unchecked cell division.
Conclude the connection: The key mechanism by which changes in the cell cycle can lead to cancer is through mutations in tumor suppressor genes, as these mutations remove the regulatory control over cell division, leading to potential tumor formation.