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Multiple Choice
What are the typical functions of proteins encoded by genes that may become oncogenes?
A
Regulating cell growth and division
B
Inhibiting angiogenesis
C
Promoting apoptosis
D
Facilitating DNA repair
Verified step by step guidance
1
Understand that oncogenes are mutated forms of genes that normally regulate cell growth and division. These mutations can lead to uncontrolled cell proliferation, a hallmark of cancer.
Recognize that proteins encoded by oncogenes may lose their ability to inhibit angiogenesis, which is the process of forming new blood vessels. This can allow tumors to receive more nutrients and oxygen, promoting their growth.
Learn that oncogenes can affect apoptosis, which is the programmed cell death that helps eliminate damaged or unnecessary cells. Mutations may prevent apoptosis, allowing cancer cells to survive longer than they should.
Explore how oncogenes might interfere with DNA repair mechanisms. Normally, proteins involved in DNA repair fix mutations that occur during cell division, but oncogenes can disrupt this process, leading to accumulation of genetic errors.
Consider the broader impact of oncogenes on cellular functions. While they primarily affect growth, division, angiogenesis, apoptosis, and DNA repair, they can also influence other pathways that contribute to cancer progression.