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Multiple Choice
Which one of the following is needed to synthesize a new strand of DNA during replication?
A
Ligase
B
RNA polymerase
C
Helicase
D
DNA polymerase
Verified step by step guidance
1
Understand the process of DNA replication: DNA replication is the process by which a double-stranded DNA molecule is copied to produce two identical DNA molecules. It is a critical process that occurs in all living organisms to ensure that each new cell receives an exact copy of the DNA.
Identify the role of DNA polymerase: DNA polymerase is the enzyme responsible for synthesizing new DNA strands by adding nucleotides to a pre-existing chain. It reads the existing DNA strand and uses it as a template to create a new complementary strand.
Differentiate between the enzymes involved in DNA replication: Ligase is involved in joining Okazaki fragments on the lagging strand, RNA polymerase synthesizes RNA, and helicase unwinds the DNA double helix. DNA polymerase, however, is specifically responsible for synthesizing the new DNA strand.
Recognize the importance of a primer: DNA polymerase requires a short RNA primer to initiate the synthesis of a new DNA strand. This primer is synthesized by an enzyme called primase.
Conclude that DNA polymerase is essential for DNA synthesis: Given the roles of the different enzymes, DNA polymerase is the enzyme directly responsible for synthesizing the new DNA strand during replication.