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Multiple Choice
The process of firing an action potential begins when a neuron is stimulated and:
A
the membrane potential becomes more negative due to K$^+$ influx
B
the membrane potential reaches the threshold, causing voltage-gated Na$^+$ channels to open
C
the sodium-potassium pump stops functioning
D
neurotransmitters are released from the axon terminal
Verified step by step guidance
1
Understand the concept of an action potential: An action potential is a rapid electrical signal that travels along the membrane of a neuron. It is initiated when the neuron is stimulated and the membrane potential changes.
Recognize the role of the threshold potential: The threshold potential is the critical level of depolarization that must be reached for voltage-gated Na⁺ channels to open. This is a key step in firing an action potential.
Explain the opening of voltage-gated Na⁺ channels: When the membrane potential reaches the threshold, voltage-gated Na⁺ channels open, allowing Na⁺ ions to flow into the cell. This influx of Na⁺ ions causes further depolarization of the membrane.
Clarify why K⁺ influx does not initiate an action potential: K⁺ ions typically move out of the cell during repolarization, not into the cell during depolarization. Therefore, K⁺ influx does not contribute to the initiation of an action potential.
Discuss the role of neurotransmitters and the sodium-potassium pump: Neurotransmitters are released from the axon terminal after the action potential reaches the end of the neuron, and the sodium-potassium pump helps restore the resting membrane potential after the action potential has occurred. Neither of these processes directly initiates an action potential.