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Multiple Choice
Which of the following is not a virulence factor of Bordetella pertussis?
A
Filamentous hemagglutinin
B
Adenylate cyclase toxin
C
Pertussis toxin
D
Capsule
Verified step by step guidance
1
Understand what virulence factors are: Virulence factors are molecules produced by pathogens (bacteria, viruses, fungi, and protozoa) that contribute to the pathogenicity and promote infection and disease in the host.
Identify the virulence factors of Bordetella pertussis: Bordetella pertussis is known to produce several virulence factors, including filamentous hemagglutinin, adenylate cyclase toxin, and pertussis toxin.
Research the role of each listed factor: Filamentous hemagglutinin helps in adhesion to host cells, adenylate cyclase toxin disrupts host immune responses, and pertussis toxin interferes with host cell signaling.
Consider the role of a capsule: A capsule is a polysaccharide layer that some bacteria have, which can protect them from phagocytosis by host immune cells. However, Bordetella pertussis does not have a capsule as a virulence factor.
Conclude which option is not a virulence factor: Since Bordetella pertussis does not use a capsule as a virulence factor, the correct answer is 'Capsule'.